6-Carboxytetramethylrhodamine

Names

[ Name ]:
6-Carboxytetramethylrhodamine

[Synonym ]:
6-Carboxytetramethylrhodamine
6-TAMRA
N,N,N',N'-Tetramethyl-6-carboxyrhodamine
9-(2,5-Dicarboxyphenyl)-3,6-bis(dimethylamino)xanthylium
Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt
2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate

Biological Activity

[Description]:

Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 6-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Melting Point ]:
NA

[ Molecular Formula ]:
C₂₅H₂₂N₂O₅

[ Molecular Weight ]:
430.453

[ Exact Mass ]:
430.152863

[ PSA ]:
97.05000

[ LogP ]:
3.72780

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.

J. Neurovirol. 21(2) , 159-73, (2015)

Recovery from encephalomyelitis induced by infection with mosquito-borne alphaviruses is associated with a high risk of lifelong debilitating neurological deficits. Infection of mice with the prototyp...

Mouse model for sublethal Leptospira interrogans infection.

Infect. Immun. 83 , 4693-700, (2015)

Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive to acute disease. Chronic disease has bee...

A Set of Cytogenetic Markers Allows the Precise Identification of All A-Genome Chromosomes in Diploid and Polyploid Wheat.

Cytogenet. Genome Res. 146 , 71-9, (2015)

Karyotypes of 3 diploid wheat species containing different variants of the A-genome, Triticum boeoticum (A(b)), T. monococcum (A(b)), and T. urartu (A(u)), were examined using C-banding and FISH with ...