AZD5099

Names

[ Name ]:
AZD5099

Biological Activity

[Description]:

AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Topoisomerase II

[References]

[1]. Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099). J Med Chem. 2014 Jul 24;57(14):6060-82.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₇Cl₂N₅O₆S

[ Molecular Weight ]:
548.44

Related Compounds

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