3′,5′-Cyclic nucleotide phosphodiesterase
Names
[ CAS No. ]:
9040-59-9
[ Name ]:
3′,5′-Cyclic nucleotide phosphodiesterase
[Synonym ]:
(4-Nitrobenzyl)arsonic acid
Arsonic acid, As-[(4-nitrophenyl)methyl]-
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Boiling Point ]:
572.9±52.0 °C at 760 mmHg
[ Molecular Formula ]:
C7H8AsNO5
[ Molecular Weight ]:
261.064
[ Flash Point ]:
253.4±19.1 °C
[ Exact Mass ]:
260.961853
[ LogP ]:
-0.25
[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C
[ Storage condition ]:
20°C
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T
[ RIDADR ]:
NONH for all modes of transport
Articles
Mol. Pharmacol. 84(6) , 787-93, (2013)
Tissue fibrosis is characterized by excessive production, deposition, and contraction of the extracellular matrix (ECM). The second messenger cAMP has antifibrotic effects in fibroblasts from several ...
Regulation of ecto-apyrase CD39 (ENTPD1) expression by phosphodiesterase III (PDE3).FASEB J. 27(11) , 4419-28, (2013)
The ectoenzyme CD39 suppresses thrombosis and inflammation by suppressing ATP and ADP to AMP. However, mechanisms of CD39 transcriptional and post-translational regulation are not well known. Here we ...
Inhibition of phosphodiesterase-1 attenuates cold-induced pulmonary hypertension.Hypertension 61(3) , 585-92, (2013)
Chronic exposure to cold caused pulmonary arterial hypertension (cold-induced pulmonary hypertension [CIPH]) and increased phosphodiesterase-1C (PDE-1C) expression in pulmonary arteries (PAs) in rats....