Hydroxypropyl Cellulose
Names
[ CAS No. ]:
9004-64-2
[ Name ]:
Hydroxypropyl Cellulose
[Synonym ]:
β-D-Glucopyranoside, 2-hydroxypropyl 2,3,6-tris-O-(2-hydroxypropyl)-4-O-[2,3,4,6-tetrakis-O-(2-hydroxypropyl)-α-D-glucopyranosyl]-
Klucel
MFCD00132688
2-Hydroxypropyl 2,3,6-tris-O-(2-hydroxypropyl)-4-O-[2,3,4,6-tetrakis-O-(2-hydroxypropyl)-α-D-glucopyranosyl]-β-D-glucopyranoside
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
891.2±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C36H70O19
[ Molecular Weight ]:
806.930
[ Flash Point ]:
492.8±34.3 °C
[ Exact Mass ]:
806.451111
[ LogP ]:
-1.24
[ Appearance of Characters ]:
powder | White to light cream
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.532
[ Stability ]:
Stable. Incompatible with strong oxidizing agents. Combustible.
[ Water Solubility ]:
polar oganic solvents: soluble
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
S24/S25
[ Safety Phrases ]:
24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
NF9050000
Articles
J. Pharm. Sci. 101(8) , 2941-51, (2012)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystal...
Stabilization of fenofibrate in low molecular weight hydroxypropylcellulose matrices produced by hot-melt extrusion.Drug Dev. Ind. Pharm. 39(2) , 290-8, (2013)
The objective of this study was to improve the dissolution rate and to enhance the stability of a poorly water-soluble and low glass-trasition temperature (T(g)) model drug, fenofibrate, in low molecu...
Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.Chem. Pharm. Bull. 60(11) , 1468-73, (2012)
In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form s...