uricase

Names

[ Name ]:
uricase

[Synonym ]:
MFCD00082126
Urate oxidase
Uric acid oxidase
Uratoxidase
Urate:O2-oxidoreductase
EINECS 232-655-5
Uricase
Uricozyme

Biological Activity

[Description]:

Urate oxidase (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Wu XW, et al. Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9412-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₆N₅O₁₄P

[ Molecular Weight ]:
567.398

[ Exact Mass ]:
567.121399

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Hardly soluble in water, slightly soluble in buffer alkaline solution.

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H334-H360FD

[ Precautionary Statements ]:
P201-P261-P280-P284-P304 + P340-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YU7100000

Articles

Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report.

Br. J. Haematol. 163(3) , 365-72, (2013)

Laboratory (LTLS) and clinical (CTLS) tumour lysis syndrome (TLS) are frequent complications in newly diagnosed children with advanced mature B cell non-Hodgkin lymphoma (B-NHL). Rasburicase, compared...

Resolution of massive tophaceous gout with three urate-lowering drugs.

Am. J. Med. 126(11) , e9-10, (2013)

Reorganizing the protein space at the Universal Protein Resource (UniProt).

Nucleic Acids Res. 40 , D71-D75, (2012)

The mission of UniProt is to support biological research by providing a freely accessible, stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.