2-Methyl-2-propanyl (2-oxoethyl)carbamate
Names
[ CAS No. ]:
89711-08-0
[ Name ]:
2-Methyl-2-propanyl (2-oxoethyl)carbamate
[Synonym ]:
Carbamic acid, N-(2-oxoethyl)-, 1,1-dimethylethyl ester
t-butyl n-(2-oxoethyl)cabamate
N-tert-butoxycarbonylglycinal
tert-butyl 2-oxoethylcarbamate
2-(t-butoxycarbonylamino)acetaldehyde
N-(tert-butoxycarbonyl)-2-amino-acetaldehyde
(2-oxo-ethyl)-carbamic acid-tert-butylester
2-Methyl-2-propanyl (2-oxoethyl)carbamate
N-Boc-2-aminoacetaldehyde
N-(tert-Butoxycarbonyl)aminoacetaldehyde
boc-l-glycinal
MFCD01321273
N-tert-butyloxycarbonyl-2-aminoacetaldehyde
(tert-butoxy)-N-(2-oxoethyl)carboxamide
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
237.2±23.0 °C at 760 mmHg
[ Molecular Formula ]:
C7H13NO3
[ Molecular Weight ]:
159.183
[ Flash Point ]:
97.3±22.6 °C
[ Exact Mass ]:
159.089539
[ PSA ]:
55.40000
[ LogP ]:
0.88
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.434
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Org. Chem. 69 , 4656-4662, (2004)
Fused heteroarylprolines were prepared starting from 4-oxo-N-(PhF)proline benzyl ester (6, PhF = 9-(9-phenylfluorenyl)) following two approaches. First, allylation of oxoproline 6 followed by Wacker o...
Tumor-targeting of EGFR inhibitors by hypoxia-mediated activation.Angew. Chem. Int. Ed. Engl. 53(47) , 12930-5, (2014)
The development of receptor tyrosine-kinase inhibitors (TKIs) was a major step forward in cancer treatment. However, the therapy with TKIs is limited by strong side effects and drug resistance. The ai...
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.Sci. Rep. 4 , 4782, (2014)
A number of Bruton's tyrosine kinase (BTK) inhibitors are currently in development, yet it has been difficult to visualize BTK expression and pharmacological inhibition in vivo in real time. We synthe...