5-(Carboxy(hydroxy)methyl)uridine methyl ester

Names

[ Name ]:
5-(Carboxy(hydroxy)methyl)uridine methyl ester

[Synonym ]:
Chmu-methyl ester

Biological Activity

[Description]:

(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. van den Born E, et al. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. Nat Commun. 2011 Feb 1;2:172.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₆N₂O₉

[ Molecular Weight ]:
332.26300

[ Exact Mass ]:
332.08600

[ PSA ]:
171.57000

Related Compounds

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