Pulegone
Names
[ CAS No. ]:
89-82-7
[ Name ]:
Pulegone
[Synonym ]:
(5R)-5-methyl-2-(methylethylidene)cyclohexan-1-one
(5R)-2-Isopropylidéne-5-méthylcyclohexanone
(R)-Pulegone
Cyclohexanone, 5-methyl-2- (1-methylethylidene)-, (R)-
PULEGON
MFCD00063000
PULEGONE,TECH
2-isopropylidene-5-methylcyclohexan-1-one
p-Menth-4(8)-en-3-one, (R)-(+)-
EINECS 201-943-2
(5R)-5-Methyl-2-(2-propanyliden)cyclohexanon
Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (5R)-
(+)-(R)-Pulegone
D-PULEGONE
R-(+)-Pulegone
Pulegone,(d)
(1R)-(+)-pulegone
(5R)-2-Isopropylidene-5-methylcyclohexanone
(+)-Pulegone
R-(+)-p-Menth-4(8)-en-3-one
FEMA 2963
Pulegone
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
224.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C10H16O
[ Molecular Weight ]:
152.233
[ Flash Point ]:
82.2±0.0 °C
[ Exact Mass ]:
152.120117
[ PSA ]:
17.07000
[ LogP ]:
2.56
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.470
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OT0261000
- CHEMICAL NAME :
- p-Menth-4(8)-en-3-one, (R)-(+)-
- CAS REGISTRY NUMBER :
- 89-82-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H16-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 236,633,1953
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H351-H412
[ Precautionary Statements ]:
P273-P301 + P312 + P330
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
2810
[ WGK Germany ]:
3
[ RTECS ]:
OT0261000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2914299000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914299000
[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Eur. J. Pharmacol. 672(1-3) , 135-42, (2011)
The present study aimed to investigate the inotropic effects of R(+)-pulegone, a monoterpene found in plant species belonging to the genus Mentha, on the mammalian heart. In electrically stimulated gu...
Synthesis of (R)-(+)-4-methylcyclohex-2-ene-1-one.J. Org. Chem. 77(20) , 9422-5, (2012)
A three-step synthesis of (R)-(+)-4-methylcyclohex-2-ene-1-one (1) from (R)-(+)-pulegone (3), proceeding in 44% overall yield, is described. The sequence comprises vinyl triflate formation, site-selec...
Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia).Nat. Prod. Res. 27(4-5) , 331-9, (2013)
The essential oil of 46 spontaneous plants of Calamintha nepeta (L.) Savi subsp. nepeta growing wild in Sud, Italy (Salento, Apulia), were investigated by GC/MS. Fifty-seven components were identified...