DPDPE

Names

[ Name ]:
DPDPE

[Synonym ]:
c[D-Pen2,5]-enkephalin
[D-Pen(2),D-Pen(5)]enkephalin
8-(3-Chlorostyryl)caffeine
1,2-Dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid, 13-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-, (4S,7S,13S)-
Tyr-D-Pen-Gly-Phe-D-Pen
(4S,7S,13S)-7-Benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(L-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
H-Tyr-c(D-Pen-Gly-Phe-D-Pen)-OH
DPDPE
13-[2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
1,2-Dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid, 13-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-, (4R,7S,13R)-
Tyr-c[D-Pen-Gly-Phe-D-Pen]OH
(4R,7S,13R)-7-Benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(L-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
[D-Pen2,5]-ENKEPHALIN
[D-Pen2-D-Pen5]-enkephaline
c[D-Pen(2)-D-Pen(5)]enkephalin

Biological Activity

[Description]:

DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

[References]

[1]. F C Tortella, et al. Anticonvulsant Effects of Mu (DAGO) and Delta (DPDPE) Enkephalins in Rats. Peptides

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1038.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₃₉N₅O₇S₂

[ Molecular Weight ]:
645.790

[ Flash Point ]:
581.9±34.3 °C

[ Exact Mass ]:
645.229065

[ PSA ]:
250.55000

[ LogP ]:
2.24

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.653

[ Storage condition ]:
-20°C

Safety Information

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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