DSS30
Names
[ CAS No. ]:
883027-32-5
[ Name ]:
DSS30
Biological Activity
[Description]:
DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease[1].
[Related Catalog]:
[In Vitro]
DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1]. Western Blot Analysis[1] Cell Line: Expressed P25 PC12tet-off cell lines Concentration: 50 μM Incubation Time: 8 hours Result: Inhibited BACE1 phosphorylation by 12%.
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C16H14ClNO3S2
[ Molecular Weight ]:
367.87