883027-32-5
883027-32-5 structure
- Name: DSS30
- Chemical Name: DSS30
- CAS Number: 883027-32-5
- Molecular Formula: C16H14ClNO3S2
- Molecular Weight: 367.87
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2022-10-12 13:32:27
- Modify Date: 2024-02-24 18:13:49
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DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease[1].
| Name | DSS30 |
|---|
| Description | DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease[1]. |
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| Related Catalog | |
| In Vitro | DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1]. Western Blot Analysis[1] Cell Line: Expressed P25 PC12tet-off cell lines Concentration: 50 μM Incubation Time: 8 hours Result: Inhibited BACE1 phosphorylation by 12%. |
| References |
| Molecular Formula | C16H14ClNO3S2 |
|---|---|
| Molecular Weight | 367.87 |