LPLRF-NH2

Names

[ Name ]:
LPLRF-NH2

Biological Activity

[Description]:

LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons[1][2][3].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vitro]

YMRF-NH2 (0.1 nM-1 μM) inhibits Forskolin-induced production of cAMP in CHO cells[4].

[In Vivo]

LPLRF-NH2 (3-15 nmol, ICV) shows anorexigenic effect in chicks[1]. LPLRF-NH2 (25-50 nM/kg, 150 μL, i.v.) increases arterial blood pressure in rats[1]. Animal Model: Chicks[1] Dosage: 3.0, 7.0 or 15 nmol Administration: Intracerebroventrical injection (ICV) injection Result: Decreased food intake. Increased number of c-Fos reactive cells in the paraventricular nucleus.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₅₃N₉O₅

[ Molecular Weight ]:
643.82

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.