Name | LPLRF-NH2 |
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Description | LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons[1][2][3]. |
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Related Catalog | |
In Vitro | YMRF-NH2 (0.1 nM-1 μM) inhibits Forskolin-induced production of cAMP in CHO cells[4]. |
In Vivo | LPLRF-NH2 (3-15 nmol, ICV) shows anorexigenic effect in chicks[1]. LPLRF-NH2 (25-50 nM/kg, 150 μL, i.v.) increases arterial blood pressure in rats[1]. Animal Model: Chicks[1] Dosage: 3.0, 7.0 or 15 nmol Administration: Intracerebroventrical injection (ICV) injection Result: Decreased food intake. Increased number of c-Fos reactive cells in the paraventricular nucleus. |
Molecular Formula | C32H53N9O5 |
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Molecular Weight | 643.82 |