Thiophene-3-carboxylic acid
Names
[ CAS No. ]:
88-13-1
[ Name ]:
Thiophene-3-carboxylic acid
[Synonym ]:
b-Thiophenic Acid
Thiophene-3-carboxylic acid
β-Thiophenecarboxylic acid
b-Thiophenecarboxylic acid
β-Thiophenic acid
EINECS 201-802-5
T5SJ CVQ
3-Carboxythiophene
MFCD00005467
3-Thiophenecarboxylic acid
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
271.1±13.0 °C at 760 mmHg
[ Melting Point ]:
136-141 °C(lit.)
[ Molecular Formula ]:
C5H4O2S
[ Molecular Weight ]:
128.15
[ Flash Point ]:
117.8±19.8 °C
[ Exact Mass ]:
127.993202
[ PSA ]:
65.54000
[ LogP ]:
1.50
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.607
[ Storage condition ]:
Refrigerated.
[ Water Solubility ]:
4.3 g/L (25 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XM8330300
- CHEMICAL NAME :
- 3-Thiophenecarboxylic acid
- CAS REGISTRY NUMBER :
- 88-13-1
- BEILSTEIN REFERENCE NO. :
- 0001994
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C5-H4-O2-S
- MOLECULAR WEIGHT :
- 128.15
- WISWESSER LINE NOTATION :
- T5SJ CVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,831,1971
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
XM8330300
[ HS Code ]:
29349990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Int. J. Mol. Sci. 9(3) , 383-93, (2008)
A new polyacetylene derivative with electroactive thiophene substituent, namely poly(2-methylbut-2-enyl thiophene-3-carboxylate) was synthesized and characterized. For this purpose, novel acetylene mo...
1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI).Bioorg. Med. Chem. Lett. 11(16) , 2061-5, (2001)
1,4-Disubstituted imidazole inhibitors of Staphylococcus aureus and Escherichia coli enoyl acyl carrier protein reductase (FabI) have been identified. Crystal structure data shows the inhibitor 1 boun...
Photochemical polymerization of thiophene derivatives in aqueous solution.Chem. Commun. (Camb.) (19) , 2222-3, (2004)
A novel method of photochemical polymerization of thiophene derivatives in aqueous solution catalyzed by potassium dichromate and initiated by illumination is described.