NU-8231
Names
[ CAS No. ]:
878022-36-7
[ Name ]:
NU-8231
Biological Activity
[Description]:
A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay; induces p53-dependent gene transcription SJSA human sarcoma cell line.
[References]
References 1. Hardcastle IR, et al. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20. 2. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43. View Related Products by Target MDM2-p53
Chemical & Physical Properties
[ Molecular Formula ]:
C26H26ClNO5
[ Molecular Weight ]:
467.95