MK-8591
Names
Biological Activity
[Description]:
MK-8591 is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively.
[Related Catalog]:
[Target]
HIV-1 (WT):0.068 nM (EC50)
HIV-1 (MDR):0.15 nM (EC50)
HIV-1 (M184V):3.1 nM (EC50)
[In Vitro]
MK-8591 (4'Ed2FA) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively[1].
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C12H12FN5O3
[ Molecular Weight ]:
293.2537832