Amino-PEG4-C1-Boc

Names

[ CAS No. ]:
864680-64-8

[ Name ]:
Amino-PEG4-C1-Boc

Biological Activity

[Description]:

Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

[ Density]:
1.051±0.06 g/cm3

[ Boiling Point ]:
386.1±32.0 °C

[ Molecular Formula ]:
C₁₄H₂₉NO₆

[ Molecular Weight ]:
307.38

Amino-PEG4-C1-Boc

Names

Biological Activity

Chemical & Physical Properties

Related Compounds