1,4-DIACETOXY-2,3-DICYANOBENZENE

Names

[ Name ]:
1,4-DIACETOXY-2,3-DICYANOBENZENE

[Synonym ]:
Benzene,1,4-diacetyloxy-2,3-dicyano
1,4-Diacetoxy-2,3-dicyanobenzene
DADCB
D0679_SIAL
3,6-Diacetoxyphthalonitrile
3.6-Diacetoxy-phthalsaeure-dinitril
2,3-Dicyanochinol-diacetat
2,3-Dicyano-1,4-hydroquinone diacetate

Biological Activity

[Description]:

1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Cook JA, et, al. Intracellular pH measurements using flow cytometry with 1,4-diacetoxy-2,3-dicyanobenzene. Cytometry. 1988 Sep;9(5):441-7.

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
447.5ºC at 760 mmHg

[ Melting Point ]:
166-167ºC(lit.)

[ Molecular Formula ]:
C₁₂H₈N₂O₄

[ Molecular Weight ]:
244.20300

[ Flash Point ]:
195.2ºC

[ Exact Mass ]:
244.04800

[ PSA ]:
100.18000

[ LogP ]:
1.28056

[ Index of Refraction ]:
1.553

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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