Uridine-d2

Names

[ Name ]:
Uridine-d2

[Synonym ]:
8.8'-Dihydroxy-5.5'-dichinolyl
[5,5'-Biquinoline]-8,8'-diol
[5,5']Bichinolyl-8,8'-diol
[5,5']biquinolyl-8,8'-diol
8.8'dihydroxy-5.5'-diquinolyl
<5',5'-2H2>uridine

Biological Activity

[Description]:

Uridine-d2 is the deuterium labeled Uridine[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₀D₂N₂O₆

[ Molecular Weight ]:
246.21400

[ Exact Mass ]:
246.08200

[ PSA ]:
124.78000

Uridine-d2

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds