4(15),5,10(14)-Germacratrien-1-ol

Names

[ CAS No. ]:
81968-62-9

[ Name ]:
4(15),5,10(14)-Germacratrien-1-ol

[Synonym ]:
(1R,5E,7S)-7-Isopropyl-4,10-bis(methylene)cyclodec-5-en-1-ol
rel-(1R,5E,7S)-7-isopropyl-4,10-bis(methylene)cyclodec-5-en-1-ol
5-Cyclodecen-1-ol, 4,10-bis(methylene)-7-(1-methylethyl)-, (1R,5E,7S)-
(1R,5E,7S)-7-Isopropyl-4,10-bis(methylene)-5-cyclodecen-1-ol

Biological Activity

[Description]:

1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Liu LL, et al. Sesquiterpenoids with Various Carbocyclic Skeletonsfrom the Flowers of Chrysanthemum indicum. J Nat Prod. 2017 Feb24;80(2):298-307.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
321.1±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₄O

[ Molecular Weight ]:
220.35

[ Flash Point ]:
134.0±20.1 °C

[ Exact Mass ]:
220.182709

[ PSA ]:
20.23000

[ LogP ]:
4.82

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.494

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2906199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2906199090

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%