Castor oil

Names

[ Name ]:
Castor oil

[Synonym ]:
1,2,3-Propanetriyl (9Z,12R,9'Z,12'R,9''Z,12''R)tris(12-hydroxy-9-octadecenoate)
MFCD00130746
Ricinolein
Glycerol triricinoleate
EINECS 232-293-8
Trypsin complex
Xenaderm
UNII-D5340Y2I9G
Optase
Olio di ricino
Venelex
UNII:D5340Y2I9G
Ricinum communis oil
9-Octadecenoic acid, 12-hydroxy-, 1,2,3-propanetriyl ester, (9Z,12R,9'Z,12'R,9''Z,12''R)-
propane-1,2,3-triyl (9Z,12R,9'Z,12'R,9''Z,12''R)tris(12-hydroxyoctadec-9-enoate)
ricinus communis oil
Castor oil [USP:JAN]
Castor oil

Biological Activity

[Description]:

Castor oil is a natural triglyceride which has a laxative effect and induces labor in pregnant females.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Biochemical Assay Reagents

Natural Products >> Others

Research Areas >> Others

[In Vivo]

Castor oil is a natural triglyceride which has a laxative effect and induces labor in pregnant females. When given castor oil, wild-type mice respond with a strong diarrhea, starting about 30 min after application. The laxative effect lasts for about 2 h[1].

[Animal admin]

Mice are used to measure the laxative effects of Castor oil and starved 16 h before the experiments. On the day of the experiment, mice are treated with the Castor oil, and the bottom of the cages is covered with white tissue paper. The weight of shapeless and watery stools is determined hourly[1].

[References]

[1]. Tunaru S, et al. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9179-84.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
879.2±65.0 °C at 760 mmHg

[ Melting Point ]:
-12ºC

[ Molecular Formula ]:
C₅₇H₁₀₄O₉

[ Molecular Weight ]:
933.430

[ Flash Point ]:
224.1±27.8 °C

[ Exact Mass ]:
932.768005

[ PSA ]:
139.59000

[ LogP ]:
17.72

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.490

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents. May be light sensitive.

[ Water Solubility ]:
<0.1 g/100 mL at 20 ºC

[ Freezing Point ]:
-10℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ RTECS ]:
FI4100000

[ HS Code ]:
1515300000

Customs

[ HS Code ]: 1515300000

Articles

Effect of castor oil enrichment layer produced by reaction on the properties of PLA/HDI-g-starch blends.

Carbohydr. Polym. 94(1) , 235-43, (2013)

Blends of entirely bio-sourced polymers, namely polylactide (PLA) and starch, have been melt-compounded by lab-scale co-extruder with castor oil (CO) as a plasticizer. The enrichment of castor oil on ...

Characterization and release kinetics of nicotinamide microemulsion-based gels.

J. Cosmet. Sci. 63(6) , 397-406, (2012)

The aim of this study was to investigate physicochemical characteristics and to determine in vitro release kinetics of prepared nicotinamide microemulsion-based gels (MBGs). Nicotinamide microemulsion...

Elucidation of density profile of self-assembled sitosterol + oryzanol tubules with small-angle neutron scattering.

Faraday Discuss. 158 , 223-38; discussion 239-66, (2012)

Small-angle neutron scattering (SANS) experiments have been performed on self-assembled tubules of sitosterol and oryzanol in triglyceride oils to investigate details of their structure. Alternative o...