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PSB 069

Names

[ CAS No. ]:
78510-31-3

[ Name ]:
PSB 069

Biological Activity

[Description]:

PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[Target]

Ki: 16~18 μM (NTPDases1, 2, 3)[1]


[In Vitro]

PSB069 is a nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

[References]

[1]. Baqi Y, et al. Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases). Purinergic Signal. 2009;5(1):91-106.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H12ClN2NaO5S

[ Molecular Weight ]:
450.82700

[ Exact Mass ]:
450.00500

[ PSA ]:
137.77000

[ LogP ]:
5.08030


Related Compounds