acedapsone
Names
[ CAS No. ]:
77-46-3
[ Name ]:
acedapsone
[Synonym ]:
Acetamin
Acedapsone
Hansolar
4,4'-diacetamidodiphenyl sulphone
4,4'-bis(acetylamino)diphenyl sulfone
N,N'-[4,4'-sulfinylbis(4,1-phenylene)]diacetamide
DADDS
Diacetyldapsone
Sulfadiamine
4,4'''-sulfonylbis(acetanilide)
4,4'-diacetylaminodiphenylsulphone
Camilan
4,4'-di-N-acetylaminodiphenyl sulfone
Sulfodiamine
Rodilone
Sulfodiamin
Chemical & Physical Properties
[ Density]:
1.362g/cm3
[ Boiling Point ]:
661ºC at 760 mmHg
[ Melting Point ]:
289-292°
[ Molecular Formula ]:
C16H16N2O4S
[ Molecular Weight ]:
332.37400
[ Flash Point ]:
353.6ºC
[ Exact Mass ]:
332.08300
[ PSA ]:
100.72000
[ LogP ]:
3.66300
[ Index of Refraction ]:
1.625
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AE7175000
- CHEMICAL NAME :
- Acetanilide, 4',4'''-sulfonylbis-
- CAS REGISTRY NUMBER :
- 77-46-3
- BEILSTEIN REFERENCE NO. :
- 2164071
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H16-N2-O4-S
- MOLECULAR WEIGHT :
- 332.40
- WISWESSER LINE NOTATION :
- 1VMR DSWR DMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 61,617,1939 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4200 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 24,149,1960