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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: Bis(4-acetamidophenyl)sulfone
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77-46-3

77-46-3 structure

77-46-3 structure

Name: acedapsone
Chemical Name: N-[4-(4-acetamidophenyl)sulfonylphenyl]acetamide
CAS Number: 77-46-3
Molecular Formula: C₁₆H₁₆N₂O₄S
Molecular Weight: 332.37400
Catalog: Chemical reagent Organic reagent Sulfone, sulfoxide compound
Create Date: 2016-01-25 10:01:41
Modify Date: 2025-08-22 13:54:35

Name	N-[4-(4-acetamidophenyl)sulfonylphenyl]acetamide
Synonyms	Acetamin Acedapsone Hansolar 4,4'-diacetamidodiphenyl sulphone 4,4'-bis(acetylamino)diphenyl sulfone N,N'-[4,4'-sulfinylbis(4,1-phenylene)]diacetamide DADDS Diacetyldapsone Sulfadiamine 4,4'''-sulfonylbis(acetanilide) 4,4'-diacetylaminodiphenylsulphone Camilan 4,4'-di-N-acetylaminodiphenyl sulfone Sulfodiamine Rodilone Sulfodiamin

Density	1.362g/cm3
Boiling Point	661ºC at 760 mmHg
Melting Point	289-292°
Molecular Formula	C₁₆H₁₆N₂O₄S
Molecular Weight	332.37400
Flash Point	353.6ºC
Exact Mass	332.08300
PSA	100.72000
LogP	3.66300
Index of Refraction	1.625

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE7175000

CHEMICAL NAME :: Acetanilide, 4',4'''-sulfonylbis-

CAS REGISTRY NUMBER :: 77-46-3

BEILSTEIN REFERENCE NO. :: 2164071

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H16-N2-O4-S

MOLECULAR WEIGHT :: 332.40

WISWESSER LINE NOTATION :: 1VMR DSWR DMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 61,617,1939 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors Blood - lymphoma, including Hodgkin's disease

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 24,149,1960

Precursor 10
103-84-4 121-60-8 7355-56-8 108-24-7
80-08-0 139-65-1 1156-50-9 5423-16-5
101-59-7 1223-31-0
DownStream 2
80-08-0 13224-79-8

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