methsuximide
Names
[ CAS No. ]:
77-41-8
[ Name ]:
methsuximide
[Synonym ]:
Celontin
1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dion
1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione
mesuximid
Mesuximide
Mesuximida
Metsuccimide
Petinutin
methsuximide
Methsuximid
Mesuximidum
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.59g/cm3
[ Boiling Point ]:
489.2ºC at 760 mmHg
[ Melting Point ]:
52-53°
[ Molecular Formula ]:
C12H13NO2
[ Molecular Weight ]:
203.23700
[ Flash Point ]:
191.7ºC
[ Exact Mass ]:
203.09500
[ PSA ]:
37.38000
[ LogP ]:
1.27090
[ Index of Refraction ]:
1.692
[ Storage condition ]:
Refrigerator
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WN2625000
- CHEMICAL NAME :
- Succinimide, N,2-dimethyl-2-phenyl-
- CAS REGISTRY NUMBER :
- 77-41-8
- BEILSTEIN REFERENCE NO. :
- 0168315
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H13-N-O2
- MOLECULAR WEIGHT :
- 203.26
- WISWESSER LINE NOTATION :
- T5VNVTJ B1 D1 DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 6,740,1954 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 1006 mg/kg
- SEX/DURATION :
- female 8-10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 38,438,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6158 No. of Facilities: 29 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 876 (estimated) No. of Female Employees: 408 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H412
[ Precautionary Statements ]:
P301 + P312 + P330
[ RIDADR ]:
NONH for all modes of transport