10-Hydroxy-2-decenoic acid

Names

[ CAS No. ]:
765-01-5

[ Name ]:
10-Hydroxy-2-decenoic acid

[Synonym ]:
10-hydroxydec-2-enoic acid
2-Decenoic acid, 10-hydroxy-
(E)-10-Hydroxydec-2-enoic acid
(2E)-10-Hydroxydec-2-enoic acid
trans-10-Hydroxy-2-decenoic Acid
(2E)-10-Hydroxy-2-decenoic acid
Queen Bee Acid
10-Hydroxy-2-decenoic acid
2-Decenoic acid, 10-hydroxy-, (2E)-
MFCD00204506

Biological Activity

[Description]:

10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

Research Areas >> Inflammation/Immunology

[References]

[1]. Yoko Honda, et al. 10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling. J Aging Res. 2015:2015:425261.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
339.2±15.0 °C at 760 mmHg

[ Melting Point ]:
53-55ºC

[ Molecular Formula ]:
C₁₀H₁₈O₃

[ Molecular Weight ]:
186.248

[ Flash Point ]:
173.1±16.9 °C

[ Exact Mass ]:
186.125595

[ PSA ]:
57.53000

[ LogP ]:
1.99

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.486

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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