Kuwanon G

Names

[ Name ]:
Kuwanon G

[Synonym ]:
8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one
Kuwanon G
Kuwanone G
kumanon G
4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-
4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-
Kuwanon
8-[(1S,5R,6S)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-4H-chromen-4-one

Biological Activity

[Description]:

Kuwanon G is a flavonoid isolated from Morus alba, acts as a bombesin receptor antagonist, with potential antimicrobial activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mihara S, et al. Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry. Biochem Biophys Res Commun. 1995 Aug 15;213(2):594-9.

[2]. Mihara S, et al. Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry. Biochem Biophys Res Commun. 1995 Aug 15;213(2):594-9.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
942.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₀H₃₆O₁₁

[ Molecular Weight ]:
692.707

[ Flash Point ]:
293.9±27.8 °C

[ Exact Mass ]:
692.225769

[ PSA ]:
209.12000

[ LogP ]:
7.06

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.708

[ Storage condition ]:
2-8°C

Related Compounds

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