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(E)-10-Hydroxy Nortriptyline maleate

Names

[ CAS No. ]:
74853-74-0

[ Name ]:
(E)-10-Hydroxy Nortriptyline maleate

[Synonym ]:
trans-10-Hydroxy Nortriptyline Maleate

Biological Activity

[Description]:

(E)-10-Hydroxy Nortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

[2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H25NO5

[ Molecular Weight ]:
395.44800

[ Exact Mass ]:
395.17300

[ PSA ]:
106.86000

[ LogP ]:
3.42000

Related Compounds