74853-74-0

74853-74-0 structure

Name: (E)-10-Hydroxy Nortriptyline maleate
Chemical Name: (Z)-but-2-enedioic acid,(11E)-11-[3-(methylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
CAS Number: 74853-74-0
Molecular Formula: C₂₃H₂₅NO₅
Molecular Weight: 395.44800
Catalog: Research Areas Neurological Disease
Create Date: 2017-08-15 01:29:47
Modify Date: 2024-01-08 16:00:55
(E)-10-Hydroxy Nortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

Name	(Z)-but-2-enedioic acid,(11E)-11-[3-(methylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
Synonyms	trans-10-Hydroxy Nortriptyline Maleate

Description	(E)-10-Hydroxy Nortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.