H-Glu(Tyr-OH)-OH

Names

[ Name ]:
H-Glu(Tyr-OH)-OH

[Synonym ]:
g-L-Glutamyl-L-tyrosine
H-GLU(TYR-OH)-OH
2-amino-5-[[1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
H-Glu-Tyr-OH

Biological Activity

[Description]:

γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase

Research Areas >> Metabolic Disease

[Target]

DPP-4:6.77 mM (IC50)

[References]

[1]. Yang J, et al. γ‐Glu‐Met synthesised using a bacterial glutaminase as a potential inhibitor of dipeptidyl peptidase IV[J]. International Journal of Food Science & Technology, 2018, 53(5): 1166-1175.

Chemical & Physical Properties

[ Density]:
1.414g/cm3

[ Boiling Point ]:
690.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₈N₂O₆

[ Molecular Weight ]:
310.30

[ Flash Point ]:
371.3ºC

[ Exact Mass ]:
310.11600

[ PSA ]:
149.95000

[ LogP ]:
0.78740

[ Index of Refraction ]:
1.606

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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