Nurr1 agonist 2

Names

[ CAS No. ]:
742058-34-0

[ Name ]:
Nurr1 agonist 2

Biological Activity

[Description]:

Nurr1 agonist 3 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 3 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 3 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ballarotto M, et al.De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66(12):8170-8177.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₄O₃S

[ Molecular Weight ]:
310.37

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.