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Lidanserin

Names

[ CAS No. ]:
73725-85-6

[ Name ]:
Lidanserin

[Synonym ]:
4-(3-{3-[4-(4-fluorobenzoyl)piperidin-1-yl]propoxy}-4-methoxyphenyl)pyrrolidin-2-one
Lidanserinum
Lidanserin
Lidanserine
( inverted exclamation markA)-4-(3-(3-(4-(p-fluorobenzoyl)piperidino)propoxy)-4-methoxyphenyl)-2-pyrrolidinone
Lidanserina
Lidanserine [INN-French]

Biological Activity

[Description]:

Lidanserin is a drug which acts as a combined 5-HT2A and α1-adrenergic receptor antagonist.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Research Areas >> Neurological Disease

[Target]

5-HT2AA and α1-adrenergic receptor


[In Vitro]

Lidanserin is a combined 5-HT2A and α1-adrenergic receptor antagonist. Lidanserin is uaed as an antihypertensive agent.

[Related Small Molecules]

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Harmine | Phenylephrine hydrochloride | Yohimbine hydrochloride | Pimavanserin | Adrenaline | Ivabradine hydrochloride | Prazosin hydrochloride | Serotonin hydrochloride | Clenbuterol hydrochloride | Sodium Ferulate | Thioridazine hydrochloride | Brexpiprazole | Phentolamine mesilate

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
658.6ºC at 760 mmHg

[ Molecular Formula ]:
C26H31FN2O4

[ Molecular Weight ]:
454.53400

[ Flash Point ]:
352.1ºC

[ Exact Mass ]:
454.22700

[ PSA ]:
67.87000

[ LogP ]:
4.06830

[ Index of Refraction ]:
1.56

[ Storage condition ]:
2-8℃

Related Compounds

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