HEPES
Names
[ CAS No. ]:
7365-45-9
[ Name ]:
HEPES
[Synonym ]:
4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid
hepesfreeacid
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid
HEPES.1/2Na
2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
EIT hydrobromide
hepes solution
1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-
4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid
GOOD'S BUFFER
HEPES
HEPES BUFFER PH 8.0
2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic acid
EINECS 230-907-9
HEPES,1M solution
MFCD00006158
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
234-238 °C
[ Molecular Formula ]:
C8H18N2O4S
[ Molecular Weight ]:
238.305
[ Exact Mass ]:
238.098724
[ PSA ]:
89.46000
[ LogP ]:
-2.67
[ Index of Refraction ]:
1.543
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents. Protect from moisture.
[ Water Solubility ]:
Soluble
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL6809000
- CHEMICAL NAME :
- 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-
- CAS REGISTRY NUMBER :
- 7365-45-9
- BEILSTEIN REFERENCE NO. :
- 0883043
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H18-N2-O4-S
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9468 No. of Facilities: 239 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3025 (estimated) No. of Female Employees: 2233 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25-S22-S36-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
TL6809000
[ HS Code ]:
29335995
Customs
[ HS Code ]: 29335995
Articles
PLoS Biol. 12(1) , e1001758, (2014)
Type III interferon (IFN-λ) exhibits potent antiviral activity similar to IFN-α/β, but in contrast to the ubiquitous expression of the IFN-α/β receptor, the IFN-λ receptor is restricted to cells of ep...
Functional consequence of the MET-T1010I polymorphism in breast cancer.Oncotarget 6(5) , 2604-14, (2015)
Major breast cancer predisposition genes, only account for approximately 30% of high-risk breast cancer families and only explain 15% of breast cancer familial relative risk. The HGF growth factor rec...
Immunomodulation by the Pseudomonas syringae HopZ type III effector family in Arabidopsis.PLoS ONE 9(12) , e116152, (2014)
Pseudomonas syringae employs a type III secretion system to inject 20-30 different type III effector (T3SE) proteins into plant host cells. A major role of T3SEs is to suppress plant immune responses ...