Effusol

Names

[ Name ]:
Effusol

[Synonym ]:
effusol

Biological Activity

[Description]:

Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN).

[2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983.

Chemical & Physical Properties

[ Density]:
1.229g/cm3

[ Boiling Point ]:
508.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₆O₂

[ Molecular Weight ]:
252.30800

[ Flash Point ]:
248.4ºC

[ Exact Mass ]:
252.11500

[ PSA ]:
40.46000

[ LogP ]:
3.81480

[ Index of Refraction ]:
1.684

Precursor & DownStream

Precursor

DownStream

Related Compounds

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