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73166-28-6

73166-28-6 structure
73166-28-6 structure
  • Name: Effusol
  • Chemical Name: 5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol
  • CAS Number: 73166-28-6
  • Molecular Formula: C17H16O2
  • Molecular Weight: 252.30800
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2017-05-30 01:24:38
  • Modify Date: 2024-01-02 11:48:13
  • Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].

Name 5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol
Synonyms effusol
Description Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].
Related Catalog
References

[1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN).

[2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983.

Density 1.229g/cm3
Boiling Point 508.9ºC at 760 mmHg
Molecular Formula C17H16O2
Molecular Weight 252.30800
Flash Point 248.4ºC
Exact Mass 252.11500
PSA 40.46000
LogP 3.81480
Index of Refraction 1.684
Precursor  3

DownStream  0