7-Aminoactinomycin D
Names
[ CAS No. ]:
7240-37-1
[ Name ]:
7-Aminoactinomycin D
[Synonym ]:
7-Aminodactinomycin
MFCD00077295
7AAD
3H-Phenoxazine-1,9-dicarboxamide, 2,7-diamino-N,N-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4, 
6-dimethyl-3-oxo-
2,7-Diamino-N,N'-bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
7-Actinomycin C1
2,7-Diamino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
3H-Phenoxazine-1,9-dicarboxamide, 2,7-diamino-N,N-bis[(6S,9R,10S,13R,18aS)-hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyc 
lohexadecin-10-yl]-4,6-dimethyl-3-oxo-
7-amino-actinomycin-D
2,7-diamino-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
7-amino-AMD
Actinomycin D,7-amino
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
1400.8±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C62H87N13O16
[ Molecular Weight ]:
1270.432
[ Flash Point ]:
801.0±34.3 °C
[ Exact Mass ]:
1269.639404
[ PSA ]:
386.00000
[ LogP ]:
-5.02
[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.664
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
chloroform: 1 mg/mL, clear, red
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AU1579000
- CHEMICAL NAME :
- Actinomycin D, 7-amino-
- CAS REGISTRY NUMBER :
- 7240-37-1
- LAST UPDATED :
- 199409
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C62-H87-N13-O16
- MOLECULAR WEIGHT :
- 1270.62
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 3 umol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,448,1983
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300
[ Precautionary Statements ]:
Missing Phrase - N15.00950417
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+: Very toxic;
[ Risk Phrases ]:
R26/27/28;R36/37/38
[ Safety Phrases ]:
26-28-36/37-45
[ RIDADR ]:
UN 3462 6
[ WGK Germany ]:
3
[ RTECS ]:
AU1579000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
Precursor & DownStream
Precursor
DownStream
Articles
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