H-Phe-Gly-OH

Names

[ CAS No. ]:
721-90-4

[ Name ]:
H-Phe-Gly-OH

[Synonym ]:
Phe-Gly-OH
Phe-glycrystalline
L-Phenylalanyl-glycin
phenylalanylglycine
Phe-Gly hydrate
L-Phe-Gly-OH
L-PHENYLALANYLGLYCINE
phenylalanyl-glycin
phenylalanineglycine
PHE-GLY

Biological Activity

[Description]:

Phe-Gly hydrate is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.259g/cm3

[ Boiling Point ]:
512.5ºC at 760 mmHg

[ Melting Point ]:
-260ºC (dec.)

[ Molecular Formula ]:
C₁₁H₁₄N₂O₃

[ Molecular Weight ]:
222.24000

[ Flash Point ]:
263.7ºC

[ Exact Mass ]:
222.10000

[ PSA ]:
92.42000

[ LogP ]:
0.84840

[ Index of Refraction ]:
1.576

[ Storage condition ]:
-20C

MSDS

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Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Hydrogen exchange equilibria in thiols.

Chem. Res. Toxicol. 25(9) , 1862-7, (2012)

Cysteine, cysteinyl-glycine, glutathione, phenylalanyl-cysteinyl-glycine, and histidyl-cysteinyl-glycine were dissolved in acidic and neutral D(2)O in the presence of the radical generator 2,2'-azobis...

Enhanced transdermal delivery of phenylalanyl-glycine by chemical modification with various fatty acids.

Int. J. Pharm. 250(1) , 119-28, (2003)

We synthesized three novel lipophilic derivatives of phenylalanyl-glycine (Phe-Gly), C4-Phe-Gly, C6-Phe-Gly and C8-Phe-Gly by chemical modification with butyric acid (C4), caproic acid (C6) and octano...

Enhancement of the small intestinal uptake of phenylalanylglycine via a H+/oligopeptide transport system by chemical modification with fatty acids.

Life Sci. 61(25) , 2455-65, (1997)

The transport characteristics of chemically modified phenylalanylglycine (Phe-Gly) with butyric acid (C4-Phe-Gly) and caproic acid (C6-Phe-Gly) were examined using rabbit intestinal brush-border membr...