Mesyl anhydride

Names

[ Name ]:
Mesyl anhydride

[Synonym ]:
methanesulfonyl methanesulfonate
MFCD00007556
Methanesulfonic acid, anhydride
Mesyl anhydride
Methanesulfonic anhydride
methanesulphonic anhydride
methylsulfonyl methanesulfonate
Methanesulfonic acid anhydride; Mesyl anhydride; Methanesulfonyl anhydride
EINECS 230-442-1
Methanesulfonic anhydrid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
289.3±9.0 °C at 760 mmHg

[ Melting Point ]:
64-67 °C(lit.)

[ Molecular Formula ]:
C₂H₆O₅S₂

[ Molecular Weight ]:
174.196

[ Flash Point ]:
128.7±18.7 °C

[ Exact Mass ]:
173.965668

[ PSA ]:
94.27000

[ LogP ]:
-0.93

[ Vapour density ]:
3.3 (vs air)

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.470

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R35

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

"Greener" Friedel-Crafts acylations: a metal- and halogen-free methodology.

Org. Lett. 13(9) , 2232-5, (2011)

The utility of methanesulfonic anhydride for promoting the Friedel-Crafts acylation reaction of aryl and alkyl carboxylic acids is disclosed. This reagent allows the preparation of aryl ketones in goo...

Study of regioselective methanesulfonylation of simple aromatics with methanesulfonic anhydride in the presence of zeolite catalysts.

Org. Biomol. Chem. 2(21) , 3150-4, (2004)

Regioselective methanesulfonylation of simple aromatics using methanesulfonic anhydride can be achieved over zeolite catalysts. For example, methanesulfonylation of toluene over various cation-exchang...