4-Fluorophenyl methyl sulfone

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
295.9±32.0 °C at 760 mmHg

[ Melting Point ]:
78-81 °C(lit.)

[ Molecular Formula ]:
C₇H₇FO₂S

[ Molecular Weight ]:
174.193

[ Flash Point ]:
132.8±25.1 °C

[ Exact Mass ]:
174.015076

[ PSA ]:
42.52000

[ LogP ]:
0.81

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.507

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2904909090

Click to get detail synthetic route

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.

J. Med. Chem. 45(1) , 219-32, (2002)

A novel series of sulfone N-formylhydroxylamines (retrohydroxamates) have been investigated as matrix metalloproteinases (MMP) inhibitors. The substitution of the ether linkage of ABT-770 (5) with a s...

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