2'-C-Methyl isoguanosine

Names

[ Name ]:
2'-C-Methyl isoguanosine

[Synonym ]:
3-Hydroadenosine, 2'-C-methyl-2-oxo-
2'-C-Methyl-2-oxo-3-hydroadenosine
MFCD25542509

Biological Activity

[Description]:

2′-β-C-Methyl isoguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Molecular Formula ]:
C₁₁H₁₅N₅O₅

[ Molecular Weight ]:
297.27

[ Exact Mass ]:
297.107330

[ LogP ]:
-1.36

[ Index of Refraction ]:
1.860

2'-C-Methyl isoguanosine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds