Gly-Gly-Gly-Gly-Gly-OH

Names

[ Name ]:
Gly-Gly-Gly-Gly-Gly-OH

[Synonym ]:
N-(N-(N-(N-Glycylglycyl)glycyl)glycyl)glycine
Gly_Gly_Gly_Gly_Gly
2-[[2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]acetyl]amino]acetic acid
MFCD00083696
EINECS 230-398-3
Gly-Gly-Gly-Gly
Gly-Gly-Gly-Gly-Gly-OH
glycylglycylglycylglycylglycine
H-(Gly)5-OH
H-GLY-GLY-GLY-GLY-GLY-OH

Biological Activity

[Description]:

Pentaglycine (Tetraglycylglycine) is a bridge containing five glycine molecules. Pentaglycine can form highly cross-linked peptidoglycan. Glucose reduced expression of pentaglycine. Pentaglycine is cleaved by lysostaphin, and occurs in the cell envelope of staphylococci[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Luo Z, et al. Reduced Growth of Staphylococcus aureus Under High Glucose Conditions Is Associated With Decreased Pentaglycine Expression. Front Microbiol. 2020 Nov 2;11:537290.

Chemical & Physical Properties

[ Density]:
1.406g/cm3

[ Boiling Point ]:
942.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₇N₅O₆

[ Molecular Weight ]:
303.27200

[ Flash Point ]:
523.7ºC

[ Exact Mass ]:
303.11800

[ PSA ]:
179.72000

[ Index of Refraction ]:
1.543

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability.

PLoS ONE 6 , e17054, (2011)

The WalKR two-component system is essential for viability of Staphylococcus aureus, a major pathogen. We have shown that WalKR acts as the master controller of peptidoglycan metabolism, yet none of th...

Modeling the electrophoresis of oligoglycines.

J. Sep. Sci. 33 , 2430-2438, (2010)

The electrophoretic mobility of low molecular mass oligoglycines is examined in this study using a "coarse-grained" bead modeling methodology [Pei, H., Allison, S. A., J. Chromatogr. A 2009, 1216, 190...

Site-specific tetrameric streptavidin-protein conjugation using sortase A.

J. Biotechnol. 152 , 37-42, (2011)

Streptavidin is tetrameric protein which has tight and specific biotin binding affinity, and streptavidin modification of proteins or small molecules is widely used for biotechnology tool. Here, we de...