KANAMYCIN SULFATE

Names

[ Name ]:
KANAMYCIN SULFATE

[Synonym ]:
D-Glucopyranoside, (1R,2R,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 6-amino-6-deoxy-, sulfate (1:1) (salt)
kanamycin acid sulfate
MFCD00070253
kanamycin mono sulphate
kanamycin sulphate
kanamycin monosulfate
(1R,2R,3S,4R,6S)-4,6-Diamino-3-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 6-amino-6-deoxy-D-glucopyranoside sulfate (1:1)
kanamycin a
kanamycin a sulfate salt
EINECS 246-933-9
kamycin

Biological Activity

[Description]:

Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Luo Q, et al. Carbon dots derived from kanamycin sulfate with antibacterial activity and selectivity for Cr6+ detection. Analyst. 2021 Mar 21;146(6):1965-1972.

[2]. YOW MD, et al. The ototoxic effects of kanamycin sulfate in infants and children. J Pediatr. 1962 Feb;60:230-42.

Chemical & Physical Properties

[ Boiling Point ]:
943.2ºC at 760 mmHg

[ Melting Point ]:
250ºC

[ Molecular Formula ]:
C₁₈H₃₈N₄O₁₅S

[ Molecular Weight ]:
582.577

[ Flash Point ]:
524.2ºC

[ Exact Mass ]:
582.205444

[ PSA ]:
365.59000

[ Appearance of Characters ]:
powder

[ Vapour Pressure ]:
0mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi,T

[ Risk Phrases ]:
R61

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NZ3225030

[ HS Code ]:
2941902000

Customs

[ HS Code ]: 2941902000

Articles

Antibiotic Susceptibility Patterns of Mycobacterium tuberculosis Isolates from Guizhou Province of China Against 13 Antituberculosis Drugs.

Microb. Drug Resist. 21 , 292-6, (2015)

A total of 92 Mycobacterium tuberculosis isolates were collected from patients with pulmonary tuberculosis (TB) in the Zunyi region between 2011 and 2012. Collected isolates were used to determine ant...

erm(B)-carrying elements in tetracycline-resistant pneumococci and correspondence between Tn1545 and Tn6003.

Antimicrob. Agents Chemother. 52 , 1285-90, (2008)

This study investigated the genetic organization of erm(B)-carrying transposons of Streptococcus pneumoniae and their distribution in tetracycline-resistant clinical isolates. By comparatively analyzi...

D.A.A. Mossel et al.

Arch. Lebensmittelhyg. 29 , 121, (1978)