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kanamycin acid sulfate

Names

[ CAS No. ]:
64013-70-3

[ Name ]:
kanamycin acid sulfate

[Synonym ]:
Kanamycin A sulfate
Kanamycin disulfate salt from Streptomyces kanamyceticus
kanamycin A sulphate
Canamycin A disulfate
canamycin monosulfate
kanA sulfate
EINECS 246-933-9
kanamycin A monosulfate

Chemical & Physical Properties

[ Melting Point ]:
>260℃

[ Molecular Formula ]:
C18H40N4O19S2

[ Molecular Weight ]:
680.65600

[ Exact Mass ]:
680.17300

[ PSA ]:
448.57000

[ Appearance of Characters ]:
white to off-white

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Soluble in aqueous solutions

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
61

[ Safety Phrases ]:
53-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29419000

Customs

[ HS Code ]: 29419000

Articles

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

PLoS Genet. 8(10) , e1002971, (2012)

Mechanosensory hair cell death is a leading cause of hearing and balance disorders in the human population. Hair cells are remarkably sensitive to environmental insults such as excessive noise and exp...

Aminoglycosides inhibit KCNQ4 channels in cochlear outer hair cells via depletion of phosphatidylinositol(4,5)bisphosphate.

Mol. Pharmacol. 79 , 51-60, (2011)

Aminoglycoside antibiotics (AGs) are severely ototoxic. AGs cause degeneration of outer hair cells (OHCs), leading to profound and irreversible hearing loss. The underlying mechanisms are not fully un...

Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes.

Nat. Commun. 6 , 7385, (2015)

Predicting evolutionary paths to antibiotic resistance is key for understanding and controlling drug resistance. When considering a single final resistant genotype, epistatic contingencies among mutat...


More Articles


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