2,6-Dihydroxyacetophenone

Names

[ CAS No. ]:
699-83-2

[ Name ]:
2,6-Dihydroxyacetophenone

[Synonym ]:
1,3-Benzenediol, 2-acetyl-
2,6-Dihydroxyacetophenone
MFCD00002270
Resorcinol, 2-acetyl-
Acetophenone, 2',6'-dihydroxy-
EINECS 211-833-6
1-(2,6-Dihydroxyphenyl)ethanone
Ethanone, 1-(2,6-dihydroxyphenyl)-
Ethanone, 1- (2,6-dihydroxyphenyl)-

Biological Activity

[Description]:

2,6-Dihydroxyacetophenone is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
262.8±20.0 °C at 760 mmHg

[ Melting Point ]:
156-158 °C(lit.)

[ Molecular Formula ]:
C₈H₈O₃

[ Molecular Weight ]:
152.147

[ Flash Point ]:
127.0±18.3 °C

[ Exact Mass ]:
152.047348

[ PSA ]:
57.53000

[ LogP ]:
2.28

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Water Solubility ]:
sparingly soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Molecular modeling and inhibition of phospholipase A2by polyhydroxy phenolic compounds

Eur. J. Med. Chem. 44 , 312-21, (2009)

Phospholipases A 2 are enzymes responsible for the hydrolysis of membrane phospholipids that release arachidonic acid, which serves as substrate for pro-inflammatory mediators, such as prostaglandins ...

Novel squalene-hopene cyclase inhibitors derived from hydroxycoumarins and hydroxyacetophenones.

Chem. Pharm. Bull. 52(10) , 1171-4, (2004)

Squalene-hopene cyclase (SHC) is a useful model enzyme for predicting molecular interactions with oxidosqualene cyclase (OSC). Structure--activity relationships were investigated for numerous coumarin...

MALDI mass spectrometry in the solution of some forensic problems.

Forensic Sci. Int. 146 Suppl , S83-5, (2004)