Agarotetrol

Names

[ Name ]:
Agarotetrol

[Synonym ]:
(5S,6R,7R,8S)-5,6,7,8-Tetrahydroxy-2-phenethyl-5,6,7,8-tetrahydro-chromen-4-one
(5S,6R,7R,8S)-5,6,7,8-Tetrahydroxy-2-(2-phenylethyl)-5,6,7,8-tetrahydro-4H-chromen-4-one
Agarotetrol
4H-1-Benzopyran-4-one, 5,6,7,8-tetrahydro-5,6,7,8-tetrahydroxy-2-(2-phenylethyl)-, (5S,6R,7R,8S)-

Biological Activity

[Description]:

Agarotetrol is a chromone derivative isolated from Agarwood.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Natural Products >> Others

Research Areas >> Others

[In Vitro]

Agarotetrol is a chromone derivative isolated from Agarwood, shows no inhibitory activity against phosphodiesterase (PDE) 3A (IC50, >100 μM).

[References]

[1]. Sugiyama T, et al. Three new 5,6,7,8-tetrahydroxy-5,6,7,8-tetrahydrochromone derivatives enantiomeric to agarotetrol from agarwood. J Nat Med. 2018 Jun;72(3):667-674.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
581.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₈O₆

[ Molecular Weight ]:
318.321

[ Flash Point ]:
216.5±23.6 °C

[ Exact Mass ]:
318.110352

[ PSA ]:
111.13000

[ LogP ]:
2.72

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.676

[ Storage condition ]:
2-8℃