6-Methylnicotinamide

Names

[ Name ]:
6-Methylnicotinamide

[Synonym ]:
3-Pyridinecarboxamide, 6-methyl-
6-methylpyridine-3-carboxamide
MFCD00006342
6-Methylnicotinamide

Biological Activity

[Description]:

6-Methylnicotinamide, a derivate of nicotinamide, is an endogenous metabolite. A sudden increase of 6-methylnicotinamide in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. En Hu, et al. Temporal metabolomic alteration in rat brains of experimental intracerebral hemorrhage. Brain Res Bull. 2021 May;170:234-245.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
289.4±28.0 °C at 760 mmHg

[ Melting Point ]:
197-199 °C(lit.)

[ Molecular Formula ]:
C₇H₈N₂O

[ Molecular Weight ]:
136.151

[ Flash Point ]:
128.8±24.0 °C

[ Exact Mass ]:
136.063660

[ PSA ]:
55.98000

[ LogP ]:
0.35

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.561

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Nicotinamide derivatives and mitochondrial respiration.

Biochem. Soc. Trans. 24(1) , 61S, (1996)

Related Compounds

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