4-Amino-2-hydroxybenzenecarbohydrazide

Names

[ Name ]:
4-Amino-2-hydroxybenzenecarbohydrazide

[Synonym ]:
4-Aminosalicylohydrazide
p-Aminosalicylhydrazide
4-aminosalicyl hydrazide
Pasdrazide
4-Amino-2-hydroxy-benzoesaeure-hydrazid
EINECS 230-108-5
p-Aminosalicylic acid hydrazide
4-amino-2-hydroxy-benzoic acid hydrazide
PAS-Hydrazid
Apacizin
4-Aminosalicylic acid hydrazide
4-Aminosalicylsaeurehydrazid

Biological Activity

[Description]:

4-Amino-2-hydroxybenzohydrazide, an asymmetric unit, comprises two crystallographically independent molecules (A and B)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. H. Kargar, et al. 4-Amino-2-hydroxybenzohydrazide.

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Molecular Formula ]:
C₇H₉N₃O₂

[ Molecular Weight ]:
167.16500

[ Exact Mass ]:
167.06900

[ PSA ]:
101.37000

[ LogP ]:
1.25030

[ Index of Refraction ]:
1.688

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO1638000

CHEMICAL NAME :: Salicylic acid, 4-amino-, hydrazide

CAS REGISTRY NUMBER :: 6946-29-8

BEILSTEIN REFERENCE NO. :: 2965831

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H9-N3-O2

MOLECULAR WEIGHT :: 167.19

WISWESSER LINE NOTATION :: ZMVR DZ BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

Safety Information

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%