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4-Nitrosalicylic Acid

Names

[ CAS No. ]:
619-19-2

[ Name ]:
4-Nitrosalicylic Acid

[Synonym ]:
2-hydroxy-4-nitrobenzoic acid
Salicylic acid, 4-nitro-
Benzoic acid, 2-hydroxy-4-nitro-
P-NITROSALICYLIC ACID
EINECS 210-584-0
4-Nitro-2-hydroxybenzoic acid
4-Nitrosalicylic Acid
MFCD00071505

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
389.0±37.0 °C at 760 mmHg

[ Melting Point ]:
235-239 °C(lit.)

[ Molecular Formula ]:
C7H5NO5

[ Molecular Weight ]:
183.118

[ Flash Point ]:
179.2±15.0 °C

[ Exact Mass ]:
183.016769

[ PSA ]:
103.35000

[ LogP ]:
2.77

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.664

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO5300100
CHEMICAL NAME :
Salicylic acid, 4-nitro-
CAS REGISTRY NUMBER :
619-19-2
BEILSTEIN REFERENCE NO. :
2213722
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H5-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZENBAX Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie. (Tuebingen, Fed. Rep. Ger.) V.2B-27B, 1947-1972. For publisher information, see ZNCBDA. Volume(issue)/page/year: 6B,183,1951
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
375 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZENBAX Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie. (Tuebingen, Fed. Rep. Ger.) V.2B-27B, 1947-1972. For publisher information, see ZNCBDA. Volume(issue)/page/year: 6B,183,1951

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VO5300100

[ HS Code ]:
2918290000

Synthetic Route

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Novel pathway for the degradation of 2-chloro-4-nitrobenzoic acid by Acinetobacter sp. strain RKJ12.

Appl. Environ. Microbiol. 77(18) , 6606-13, (2011)

The organism Acinetobacter sp. RKJ12 is capable of utilizing 2-chloro-4-nitrobenzoic acid (2C4NBA) as a sole source of carbon, nitrogen, and energy. In the degradation of 2C4NBA by strain RKJ12, vario...


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