SABA1

Names

[ Name ]:
SABA1

Biological Activity

[Description]:

SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

SABA1 inhibits BC via an atypical mechanism. It binds in the biotin binding site in the presence of ADP and represents a potentially antibiotic used to combat the antibacterial resistance crisis[1].

[References]

[1]. Matthew K Craft, et al. Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate. J Enzyme Inhib Med Chem. 2022 Dec;37(1):100-108.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₉ClN₂O₅S

[ Molecular Weight ]:
458.91

Related Compounds

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