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690681-65-3

690681-65-3 structure

690681-65-3 structure

Name: SABA1
Chemical Name: SABA1
CAS Number: 690681-65-3
Molecular Formula: C₂₂H₁₉ClN₂O₅S
Molecular Weight: 458.91
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-06-22 18:58:27
Modify Date: 2024-01-13 22:57:52
SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC[1].

Name	SABA1

Description	SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	SABA1 inhibits BC via an atypical mechanism. It binds in the biotin binding site in the presence of ADP and represents a potentially antibiotic used to combat the antibacterial resistance crisis[1].
References	[1]. Matthew K Craft, et al. Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate. J Enzyme Inhib Med Chem. 2022 Dec;37(1):100-108.

Molecular Formula	C₂₂H₁₉ClN₂O₅S
Molecular Weight	458.91